Enzymatic analysis of uridine diphosphate N-acetyl-d -glucosamine
نویسندگان
چکیده
منابع مشابه
Pathway of Uridine Diphosphate N-Acetyl-d-Glucosamine Biosynthesis in Phaseolus aureus.
Studies with extracts obtained from mung beans (Phaseolus aureus) showed that UDP-N-acetyl d-glucosamine is formed from d-fructose 6-phosphate by a series of the following enzymic reactions: [Formula: see text]UDP-N-acetyl-d-glucosamine inhibits the first reaction in the multistep pathway leading to its biosynthesis.
متن کاملEnzymatic Synthesis of Uridine Diphosphate Xylose and Uridine Diphosphate Arabinose.
It has been shown previously' that mung bean seedlings contain a mixture of sugar nucleotides consisting of UDPG,2 UDPGal, UDPXy, and UDPAr. In the present communication evidence is presented that these bean seedlings contain an enzymatic system capable of catalyzing the reversible formation of UDPXy and UDPAr from UTP and a-D-Xy-l-P. When a-D-Xy-l-P and UTP were incubated in the presence of an...
متن کاملA novel uridine nucleotide containing N-acetyl-glucosamine and galactose.
While the yolk traverses the hen oviduct, albumen, shell membranes, and the calcified shell are successively secreted (3). The isthmus, a short section 2 to 8 cm in length, synthesizes and secretes the inner shell membrane, a lace-like envelope composed of fibers of an acid glycoprotein (see below). A number of nucleotides have been shown to occur in the isthmus, including cytosine diphosphate ...
متن کاملMetabolism of D-glucosamine and N-acetyl-D-glucosamine in the intact rat.
It has been demonstrated that n-glucosamine and N-acetyln-glucosamine are metabolized in animal tissues to n-fructose via phosphorylated intermediates (14). It has also been shown that n-glucose is converted to n-glucosamine and incorporated into glycoproteins and mucopolysaccharides (Pll), probably through formation of uridine diphosphate derivatives as intermediates (4). Little work has been ...
متن کاملSynthesis of oseltamivir and tamiphosphor from N-acetyl-D-glucosamine.
Using N-acetyl-D-glucosamine as a starting material, the anti-influenza drugs oseltamivir and tamiphosphor were synthesized via a pivotal intermediate of aldehyde 8. An intramolecular Horner-Wadsworth-Emmons reaction was utilized to construct the highly functionalized cyclohexene ring. The existing N-acetyl group was transformed into an azido group for the subsequent aziridination, followed by ...
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ژورنال
عنوان ژورنال: Analytical Biochemistry
سال: 2008
ISSN: 0003-2697
DOI: 10.1016/j.ab.2008.06.034